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Transforming ITP Care: Implementing Durable, Patient-Centered Treatment Strategies in Practice

Downloadable slides on the evolving management of immune thrombocytopenia (ITP), including disease pathophysiology, treatment-related burden, and current guideline-based approaches across lines of therapy. The slides review evidence for established options such as corticosteroids, rituximab, thrombopoietin receptor agonists (TPO-RAs), fostamatinib, and splenectomy, as well as clinical trial data for newer and emerging immune-targeted therapies, including rilzabrutinib, ianalumab, efgartigimod, and mezagitamab. Key studies reviewed include LUNA 3, VAYHIT1/2/3, and ADVANCE IV, with attention to platelet response, treatment failure, fatigue, bleeding, safety, and sustained response off treatment. The slides also emphasize durability-focused treatment goals, TPO-RA tapering, and shared decision-making to help individualize therapy according to disease control, treatment burden, adverse effects, and patient preferences.

Transforming ITP Care

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Released: October 02, 2026